Maysville 

Maysville, a small village near the center of West Salem township, is located a few miles west of Greenville, in the northwest corner of Mercer County.  

Maysville was a trading spot in the early 1800s, but it hasn't always been called Maysville.  Big Run, a stream that runs through the town was once known as Mays Creek.  The part of town on the west side of the creek was called Maysville; the part on the east side was called Maysdale.  The town was called Meadows for a time in the early 1900s, but the name reverted back to Maysville.

West Salem township's first gristmill was built in 1829 in Maysville by John Gravat.  It used water from Big Run.  The West Salem Baptist Church erected a building in 1840.  Thomas McMahan built a sawmill in 1846 and then built a steam-operated gristmill in 1848.   He ran the mill for 20 years.  It later burned down.  In 1877, Nimrod Burwell owned the land where the mill once stood. In 1873, John Russell built a cheese factory in Maysville, it burned down twice and was later replaced by one built by J. W. Woods.  

The post office was established in Maysville in 1852; it was discontinued in 1872.  An old map showed that six roads met at Maysville and the town had become a community center with a store, hotel and blacksmith shop, in addition to the cheese factory and the various mills on Big Run.  It was also a stagecoach stop between Warren, OH, and Franklin, PA.  The town had succession of early blacksmiths, including one identified only in records as Bittenbanner, a man who had the dubious distinction of having a wooden leg he carved from a log.

History of Mercer County, 1877, p. 85.